This is called Acanthosis nigricans (AN). Common comorbidities are obesity, insulin resistance, and a strong family history of type 2 diabetes. AN ranges in appearance from diffuse streaky thickened brown velvety lesions to leathery verrucous papillomatous lesions.
Patients with AN are at higher risk of metabolic syndrome, and lipid screening should be considered along with consideration of testing for DM. Keratolytic agents (e.g., salicylic acid) can improve the cosmetic appearance. Metformin and octreotide have also been used to manage AN.
This is called Acanthosis nigricans (AN). Common comorbidities are obesity, insulin resistance, and a strong family history of type 2 diabetes. AN ranges in appearance from diffuse streaky thickened brown velvety lesions to leathery verrucous papillomatous lesions.
ReplyDeletePatients with AN are at higher risk of metabolic syndrome, and lipid screening should be considered along with consideration of testing for DM. Keratolytic agents (e.g., salicylic acid) can improve the cosmetic appearance. Metformin and octreotide have also been used to manage AN.